Ideal for limited amount of material

STYL’One Nano Benchtop Compaction Simulator


Tableting has never been so easy to investigate, from pure API characterization to formulation assessment. The STYL’One Nano includes in a small footprint the unique and powerful drive technology, normally reserved for an elite of premium compaction simulators. Scientists can use the flexibility to drive the punches at high velocity to replicate the pre and main compression of an R&D rotary tablet press. The powerful Alix data acquisition and analysis software allows to screen a formulation in less than 5 minutes.

R&D
Single-Layer
tablet press

SINGLE-PUNCH PRESS

SINGLE-LAYER

MAX. 50 KN

FULL INSTRUMENTATION & DATA ANALYSIS

Designed for Pharma & Nutraceuticals

The STYL’One Nano is a compact tabletop unit that is easy to clean due to a GMP working area featuring smooth surfaces and full accessibility. It permits very small material quantities to be utilized and characterized very quickly with a minimum of set-up. With a range of options and accessories the STYL’One Nano is a flexible research tool.

Versatility

The STYL’One Nano covers the following fields of applicaton:

  • API / Excipient characterization: work with minimal material quantities to assess material attributes and compare different material suppliers
  • Analytical development: sample production for analytical method development and validation
  • Formulation feasibility and optimization: evaluate effect of Process Parameters (PP), assess Quality Attributes (QA) or produce early stability batches

Advanced Instrumentation

The STYL'One Nano is designed with the most advanced instrumentation to measure the upper and lower compression force and punch position. Mechanical deformation is automatically measured and compensated for by the software.
Standard instrumentation consists of:

  • Precompression force
  • Main compression force
  • Ejection force
  • Upper punch displacement
  • Lower punch displacement

Powerful data acquisition and analysis software

The software Alix controls the STYL’One Nano, collects, computes and analyzes the generated data by plotting a wide range of parameters including manufacturability, tabletability, compressibility and compactibility. Customized plots for any data parameters are easily developed. The HMI simplifies the design and execution of experiments. Tablet tester data can be uploaded and graphs generated.

Flexible Tooling

The machine permits the use of standard EU/TSM B, BB, BBS and D tooling of any shapes, including multi-tip and oversized tooling. The STYL’One Nano permits a wide range of tablet formats, including mini-tablets of 2 mm to a maximum tablet diameter of 40 mm.

  • Simple tool setup and exchange
  • Minimal parts to assemble
  • Change over in 5 minutes
  • Up to 40 mm diameter oversized tooling

Filling Solutions

With a wide range of filling options, the STYL’One Nano is a flexible research tool that can easily be adapted to the amount and type of product to be processed. 

  • Manual filling: only a few grams of material 
  • Gravity feeder: low amount of material
  • Forced feeder: challenging formulation and/or mini-tablets

Simulation of R&D rotary tablet presses

At the heart of the STYL’One is a powerful drive system controlled by the Alix software, which supports high punch acceleration and velocity required to simulate R&D rotary press kinetics. The STYL’One Nano features up to 50 kN precompression and main compression capability. The possibility to apply a precompression allows testing its impact on formulation. The machine allows the simulation of R&D rotary tablet presses with different compression profiles, like V-shape or extended dwell time.

Quick Changeover

The STYL’One Nano can be setup in less than 5 minutes. Due to the streamlined design of the compression zone only a limited number of components need to be removed ensuring a higher level of serviceability. The working area permits a fast and easy cleaning. All optional accessories are just as easy to install.

Containment Solutions


KORSCH offers a wide range of containment solutions on most machine models, including DryCon® and WipCon® executions. With  proven  solutions  across  the  full  containment  range (OEB 3, OEB 4, OEB 5), KORSCH provides a fully turnkey system which is engineered to meet the specific requirements of the project. In partnership with the customer, KORSCH specialists define critical process parameters, including containment requirements, peripheral integration, and automation design. KORSCH engineers are expert in developing the concept, execution, integration, and final SMEPAC testing to fully validate the containment capability.

STYL’One Nano WipCon®

The STYL’One Nano WipCon® offers a full high-containment and Wash-in-Place capability and is ideal for potent product characterization and scale-up. Offering a range of press profiles including precompression, the STYL’One Nano can replicate a small-scale rotary press. An advanced data acquisition system permits automated analysis to streamline product development.

LEARN MORE

STYL' One Nano Downloads

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Rich Ferreira
Contact
KORSCH America Inc.
Rich Ferreira
Sales
South Easton, MA 02375
USA
Matt Morganelli
Contact
KORSCH America Inc.
Matt Morganelli
Sales
South Easton, MA 02375
USA
Garrett Mann
Contact
KORSCH America Inc.
Garrett Mann
Sales
USA
Ben McGandy
Contact
KORSCH America Inc.
Ben McGandy
Customer Care
South Easton, MA 02375
USA